Architecture, in the history of humanity, is linked to the life trajectory of human beings. The architectural typology of care institutions represent, in this way, documents, material testimonies of the social coexistence of cultures in distinct eras, which, when erased, contribute to the silencing of important testimonials. In the case of isolated hospitals, their destruction also buried unheard voices that could have narrated the experiences of pain experienced in these local areas. This is the case with Sanatorium Domingos Freire, the first sanatorium of the city of Belém, inaugurated in 1901 and demolished in 1959. Silenced material testimony, the space of “certain death” represented not only an environment of separation, but also the hygienist disposition between “clean and dirty”, which carried in its architectural outline important sources of understanding about assistance architecture. This study aims to bring to light the written documents and iconography and provide the understanding of their function and role in epidemic care in the city of Belem.