This article analyzes the evolution and relationship of different communicative elements in hospital facades of the Iberian Peninsula during the fifteenth and sixteenth centuries. Iconography was present for the identification of these institutions within the urban framework, while heraldry was used as a representative extension of the sponsors. To this was added the use of monumental writings which employed gothic and humanistic letters as well as identifying and commemorative functions. This process of integration and dialogue of writing together with heraldry and iconography resulted in the incorporation of emblems by hospitals, a symbol that brought together multiple meanings.